Magnetic resonance imaging (MRI) can provide a number of measurements relevant to sport-related concussion (SRC) symptoms; however, most studies to date have used a single MRI modality and whole-brain exploratory analyses in attempts to localize concussion injury. This has resulted in highly variable findings across studies due to wide ranging symptomology, severity and nature of injury within studies. A multimodal MRI, symptom-guided region-of-interest (ROI) approach is likely to yield more consistent results. The functions of the cerebellum and basal ganglia transcend (...) many common concussion symptoms, and thus these regions, plus the white matter tracts that connect or project from them, constitute plausible ROIs for MRI analysis. We performed diffusion tensor imaging (DTI), resting-state functional MRI, quantitative susceptibility mapping (QSM), and cerebral blood flow (CBF) imaging using arterial spin labeling (ASL), in youth aged 12-18 years following SRC, with a focus on the cerebellum, basal ganglia and white matter tracts. Compared to controls similar in age, sex and sport (N = 20), recent SRC youth (N = 29; MRI at 8 ± 3 days post injury) exhibited increased susceptibility in the cerebellum (p = 0.032), decreased functional connectivity between the caudate and each of the pallidum (p = 0.035) and thalamus (p = 0.021), and decreased diffusivity in the mid-posterior corpus callosum (p < 0.038); no changes were observed in recovered asymptomatic youth (N = 16; 41 ± 16 days post injury). For recent symptomatic-only SRC youth (N = 24), symptom severity was associated with increased susceptibility in the superior cerebellar peduncles (p = 0.011) and reduced activity in the cerebellum (p = 0.013). Fewer days between injury and MRI were associated with reduced cerebellar-parietal functional connectivity (p < 0.014), reduced activity of the pallidum (p = 0.002), increased CBF in the caudate (p = 0.005), and reduced diffusivity in the central corpus callosum (p < 0.05). Youth SRC is associated with acute cerebellar inflammation accompanied by reduced cerebellar activity and cerebellar-parietal connectivity, as well as structural changes of the middle regions of the corpus callosum accompanied by functional changes of the caudate, all of which resolve with recovery. Early MRI post-injury is important to establish objective MRI-based indicators for concussion diagnosis, recovery assessment and prediction of outcome. (shrink)

Philosophical work on truth covers two streams of inquiry, one concerning the nature (if any) of truth, the other concerning truth-related paradox, especially the Liar. For the most part these streams have proceeded fairly independently of each other. In his "Deflationary Truth and the Liar" (JPL 28:455-488, 1999) Keith Simmons argues that the two streams bear on one another in an important way; specifically, the Liar poses a greater problem for deflationary conceptions of truth than it does for inflationist (...) conceptions. We agree with Simmons on this point; however, we disagree with his main conclusion. In a nutshell, Simmons' main conclusion is that deflationists can solve the Liar only by compromising deflationism. If Simmons is right, then deflationists cannot solve the Liar paradox. In this paper we argue that, pace Simmons, there is an approach to the Liar that is available to deflationists, namely dialetheism. (shrink)

The lead-off essay by Kenneth Minogue is an Oakeshottian reflection on the extent to which modern people have become passive spectators of action, detached from traditional loyalties and modes of identity and thus a kind of new Epicurean, shorn of the genuinely contemplative character of the originals. Eric Ormsby follows this with a judicious appraisal of the possibilities and perils for culture associated with the advent of the new information technology. Anthony Daniels provides a similarly sober account of the many (...) consequences and dilemmas of medical technology for the noble Hippocratic art. David Pryce-Jones’s essay recounts the antipolitical utopianism of the totalitarian ideologies that shadowed most of the twentieth century and worries about the potentially destructive utopian tendencies in the contemporary project of European integration. Keith Windschuttle surveys the range of ideologies currently deployed in the academy, most of which derive from vulgarizations of Nietzsche. Edward Said’s influential body of work comes in for particular scrutiny here. Mark Steyn contributes a discussion of the now all-too-familiar self-hatred of Western intellectuals with the blunt precision and wit so characteristic of his splendid newspaper columns. Martin Greenberg’s essay on Burke manages to educe in brief compass the understanding of freedom that is the animating heart of that exemplary statesman’s thought and practice. Diana Schaub makes a case for the importance of political philosophy to the practice of modern politics centered on the statesmanship of Lincoln. Robert Bork’s chapter on the “adversary judiciary” limns the extent to which judges have gone from being the guarantors of the rule of law to the most effective antagonists of traditional institutions and values. Finally, Roger Kimball fittingly recalls the original Ciceronian understanding of culture as the development of the mind analogous to the cultivation of the earth, and connects it with the celebrated program of criticism proposed by Matthew Arnold. (shrink)

Proponents of the public goods argument ('PGA') seek to ground the authority of the state on its putative indispensability as a means of providing public goods. But many of the things we take to be public goods – including many of the goods commonly invoked in support of the PGA – are actually what we might term publicized goods. A publicized good is any whose ‘public’ character results only from a policy decision to make some good freely and universally available. (...) This fact poses complications for the PGA, insofar as the set of possible publicized goods is quite extensive indeed. (shrink)

The Intergovernmental Panel on Climate Change has developed a novel framework for assessing and communicating uncertainty in the findings published in their periodic assessment reports. But how should these uncertainty assessments inform decisions? We take a formal decision-making perspective to investigate how scientific input formulated in the IPCC’s novel framework might inform decisions in a principled way through a normative decision model.

Though sometimes maligned, “trolleyology” offers an effective means of opening and framing, not only classes in ethics, but indeed any introductory philosophy course taking a broadly “puzzle-based” approach. When properly sequenced, a subset of the thought experiments that are trolleyology’s stock-in-trade can generate a series of puzzles illustrating the shortcomings of our untutored moral intuitions, and which thus motivate the very enterprise of moral theorizing. Students can be engaged in the attempt to resolve said puzzles, inasmuch as they’re accessible and (...) compelling, and their resolutions generally easy to achieve. Once thus engaged, students can be directed to the fact that they had already rolled up their sleeves and begun “doing philosophy.” In this way, engagement with trolleyological puzzles can serve as a “microcosm” for philosophy more broadly, illustrating the processes of critical thinking that are likewise the stock-in-trade of philosophers across many different domains of inquiry. (shrink)

Ideal for introductory ethics courses, The Moral Life: An Introductory Reader in Ethics and Literature, Fifth Edition, brings together an extensive and varied collection of ninety-one classical and contemporary readings on ethical theory and practice. Integrating literature with philosophy in an innovative way, this unique anthology uses literary works to enliven and make concrete the ethical theory or applied issues addressed. It also emphasizes the personal dimension of ethics, which is often ignored or minimized in ethics anthologies. The readings are (...) enhanced by chapter introductions, study questions, suggestions for further reading, and biographical sketches. The fifth edition adds ten new readings, eight of which appear in two new chapters: Feminist Ethics and the Ethics of Care and Global Economic Justice. An updated Companion Website at www.oup.com/us/pojman provides self-quizzes, essay questions, and helpful links for students and reading summaries, a test bank, and PowerPoint-based lecture slides for instructors. (shrink)

The Power of Critical Thinking: Effective Reasoning About Ordinary and Extraordinary Claims explores the essentials of critical reasoning, argumentation, logic, and argumentative essay writing while also incorporating important topics that most other texts leave out, such as "inference to the best explanation," scientific reasoning, evidence and authority, visual reasoning, and obstacles to critical thinking.The text integrates many pedagogical features, including hundreds of diverse exercises, examples, and illustrations; text boxes that apply critical thinking to student experience; step-by-step guidelines for evaluating claims, (...) arguments, and explanations; a glossary of important terms; and many reminders, summaries, and review notes. New to this editionNew sections on topics suggested by reviewers - The coverage now includes more discussion of legal reasoning, rhetorical ploys, informal fallacies, probability and statistics, and necessary and sufficient conditions.New Essays for Analysis - Nine essays, several of them by women authors, have been added to the collection of "Essays for Evaluation" in Appendix A, each article accompanied by writing prompts and linked to writing assignments in every chapter. Four pairs of essays are arranged in a pro/con format, each pair debating a single issue. New topics include homosexuality, feminists and pornography, adultery, airport security screenings, women in Afghanistan, Islamic extremists and free speech, and fear of vaccines.New text boxes on current topics. The division of labor for the text boxes is the same, but some of the content is new. The three types of boxes are "Newsmakers" ; "From the Web" ; and "Further Thought".The chapter objectives now correspond to the point-by-point summary at the end of each chapter.Important Clarifications - The following discussions are now even clearer: scientific conservatism in theory choice, the relationship between enumerative induction and statistical syllogisms, and informal fallacies.Some new discussions: the straw man fallacy, biased opinion polls, dishonest political discourse, and gut reactions and intuitions. (shrink)

I argue that much current thinking on externalities—at least among “lay political economists” (but even, on occasion, among professional economists)—is saddled with two analytical errors. The first is what I call coextensivism: the conflation of public goods and externalities. The second error is what I call externality profligacy: the conflation of economic and “social” externalities. The principal dangers presented by these two “dogmas on externalities” are that, while in their grips, we are under-disposed to seek negotiated, market-based solutions (of a (...) broadly Coasean nature) to challenges posed by economic externalities, and over-disposed to seek coercive, state-based solutions (of a broadly Pigouvian nature) to challenges posed by social externalities. (shrink)

Addressing Merleau-Ponty's work Phenomenology of Perception, in dialogue with The Visible and the Invisible, his lectures at the Collège de France, and his reading of Proust, this book argues that at play in his thought is a philosophy of “ontological lateness”. This describes the manner in which philosophical reflection is fated to lag behind its objects; therefore an absolute grasp on being remains beyond its reach. Merleau-Ponty articulates this philosophy against the backdrop of what he calls “cruel thought”, a style (...) of reflecting that seeks resolution by limiting, circumscribing, and arresting its object. By contrast, the philosophy of ontological lateness seeks no such finality-no apocalypsis or unveiling-but is characterized by its ability to accept the veiling of being and its own constitutive lack of punctuality. To this extent, his thinking inaugurates a new relation to the becoming of sense that overcomes cruel thought. Merleau-Ponty's work gives voice to a wisdom of dispossession that allows for the withdrawal of being. Never before has anyone engaged with the theme of Merleau-Ponty's own understanding of philosophy in such a sustained way as Whitmoyer does in this volume. (shrink)

Gene discovery reveals new biology, expands the utility of marker‐assisted selection, and enables targeted mutagenesis. Still, such discoveries can take over a decade. We present a general strategy, “Agile Genetics,” that uses nested, structured populations to overcome common limits on gene resolution. Extensive simulation work on realistic genetic architectures shows that, at population sizes of >5000 samples, single gene‐resolution can be achieved using bulk segregant pools. At this scale, read depth and technical replication become major drivers of resolution. Emerging enrichment (...) methods to address coverage are on the horizon; we describe one possibility – iterative depth sequencing (ID‐seq). In addition, graph‐based pangenomics in experimental populations will continue to maximize accuracy and improve interpretation. Based on this merger of agronomic scale with molecular and bioinformatic innovation, we predict a new age of rapid gene discovery. (shrink)

Methodological pluralism is advocated in this book, which takes students on an investigative tour of uncertainty in the social sciences, with particular emphasis on the scientific response to uncertainty. Much of the material is drawn from the disciplines of international relations and politics.

Discusses the rationality of the Christian religion and examines the philosophical arguments for the existence of God.

Learn to think critically with the leading introduction to reasoning and argumentation. Highlights In clear, reader-friendly language, The Power of Critical Thinking provides an engaging introduction to argumentation, deductive and inductive reasoning, inferencing, and evaluating scientific theories New Critical Thinking and the Media boxes in each chapter apply the principles of critical thinking to the realms of media, advertising, and news New content on "fake news," the COVID-19 pandemic, and other important contemporary topics reflects the changing world in which today's (...) students must apply their critical thinking abilities New and updated exercises offer extensive opportunities for students to practise the skills through which they will become active, engaged critical thinkers Additional online resources-including a study guide and practice quizzes for students as well as an instructor's manual, a test bank, and PowerPoint slides for instructors-offer stimulating materials to enhance the learning and teaching experiences. About the Authors Chris MacDonald is an associate professor and chair of the Law and Business Department at the Ted Rogers School of Management, Toronto Metropolitan University. Lewis Vaughn is an independent scholar and author of several textbooks on philosophy, ethics, and critical thinking. (shrink)

Condorcet's understanding of the application of the philosophy of natural sceince to social science.

These essays critically reassess the widely accepted view that statistical methods of analysis can, and do, yield causal understanding of social phenomena. They emphasize the historical, philosophical and conceptual perspectives that underlie and inform current methodological controversies.

A short definitive account of Keith Ward's theology, based on the philosophy of Personal Idealism. It records Ward's views about God, revelation, the kingdom of God, life after death, the incarnation, atonement, and Trinity. In summary, it is a concise and clear account of most central Christian doctrines, formed in the light of modern science and Idealist philosophy.

In the mathematics education research literature, there is a growing body of scholarship on how mathematicians practice their craft. The purpose of this chapter is to survey some of this literature and explain how it can contribute to the philosophy of mathematical practice. We first describe how mathematics educators use empirical methodologies to investigate the behaviors of mathematicians and argue that findings from these studies can inform the philosophy of mathematical practice. We then illustrate this by summarizing research on mathematicians’ (...) understandings and mathematicians’ proof reading. (shrink)

Asl. Atthasalinl of Buddhaghosa, ed. PTS. 1897. BB. Bibliotheca Buddhica, Petrograd. BC. Buddhacarita, ed. Cowell, Oxford, 1893. BCA. ...

This article presents the case for an approach to consciousness that I call illusionism. This is the view that phenomenal consciousness, as usually conceived, is illusory. According to illusionists, our sense that it is like something to undergo conscious experiences is due to the fact that we systematically misrepresent them as having phenomenal properties. Thus, the task for a theory of consciousness is to explain our illusory representations of phenomenality, not phenomenality itself, and the hard problem is replaced by the (...) illusion problem. Although it has had powerful defenders, illusionism remains a minority position, and it is often dismissed as failing to take consciousness seriously. This article seeks to rebut this accusation. It defines the illusionist programme, outlines its attractions, and defends it against some common objections. It concludes that illusionism is a coherent and attractive approach, which deserves serious consideration. (shrink)

The Progressive favors extending the legal institution of marriage so as to include same-sex unions along with heterosexual ones. The Traditionalist opposes such an extension, preferring to retain the legal institution of marriage in its present form. I argue that the Progressive ought to broaden her position, endorsing instead the Liberal case for extending the current institution so as to include polygamous unions as well—for any consideration favoring Progressivism over Traditionalism likewise favors Liberalism over Progressivism. Progressives inclined to resist Liberalism (...) are invited to consider an alternative position: the Libertarian stance that favors instead the ‘disestablishment’ of marriage. (shrink)

The dispute between Kantians and Humeans over whether practical reason can justify moral reasons for all agents is often characterized as a debate over whether reasons are hypothetical or categorical. Instead, this debate must be understood in terms of the distinction between agent-neutral and agent-relative reasons. This paper considers Alan Gewirth’s Reason and Morality as a case study of a Kantian justification of morality focused on deriving categorical reasons from hypothetical reasons. The case study demonstrates first, the possibility of categorical (...) agent-relative reasons, and second, that inattention to this possibility has caused considerable confusion in the debate between Kantians and Humeans. (shrink)

Mind and Supermind offers an alternative perspective on the nature of belief and the structure of the human mind. Keith Frankish argues that the folk-psychological term 'belief' refers to two distinct types of mental state, which have different properties and support different kinds of mental explanation. Building on this claim, he develops a picture of the human mind as a two-level structure, consisting of a basic mind and a supermind, and shows how the resulting account sheds light on a (...) number of puzzling phenomena and helps to vindicate folk psychology. Topics discussed include the function of conscious thought, the cognitive role of natural language, the relation between partial and flat-out belief, the possibility of active belief formation, and the nature of akrasia, self-deception and first-person authority. This book will be valuable for philosophers, psychologists and cognitive scientists. (shrink)

Contextualism has been hotly debated in recent epistemology and philosophy of language. The Case for Contextualism is a state-of-the-art exposition and defense of the contextualist position, presenting and advancing the most powerful arguments in favor of the view and responding to the most pressing objections facing it.

Recent debate regarding transgender persons’ bathroom-utilization prerogatives raises broader issues concerning current practices of sex segregation more generally. I argue that the only consistently Progressive position on bathroom access is an outright opposition to any form of bathroom segregation. This opposition, in turn, entails a thorough-going rejection of all types of sex- and gender-segregation. I then suggest that Progressives uncomfortable with such wide-ranging implications may wish to consider the merits of a certain Traditionalist position on such matters—one that counsels caution (...) and legislative forbearance when it comes to overturning long-standing customs (such as those embodied in current practices of sex-segregation). (shrink)

The pluralist liberal defends a conception of liberal politics grounded in the thesis of value pluralism. Since he argues from a particular metaphysical thesis – value pluralism – to a particular understanding of politics – liberalism – his account will feature two separable, but interrelated, components: a distinctive justification of liberalism, and a conception of politics with distinctive content. The particular flavor of liberalism to which the pluralist is led is a species of what I term “accommodationism” – an understanding (...) that sees as a polity’s central task the accommodation of many divergent conceptions of the good life. I argue that the pluralist liberal’s case is hampered by four difficulties. Two of these difficulties challenge the justification of liberalism in terms of value pluralism, and two of them plague the particular accommodationist understanding of liberalism to which the pluralist is led. I conclude by arguing that classical liberalism is a view that is immune to these latter two criticisms. In fact, I suggest a more general claim: that classical liberalism provides the most promising resources for the articulation and defense of a conception of politics dedicated to accommodating the diverse and heterogeneous versions of human flourishing countenanced by value pluralism. (shrink)

We all have different “tastes” for different tastes: some of us have a sweet tooth, while others prefer more subtle flavors; some crave spicy foods, while others cannot stand them. As Bourdieu and others have pointed out, these varying judgments seem to be more than mere preferences; often they reflect (and partially constitute) differences of class and culture. But I want to suggest that we’ve possibly overlooked another important source of these divergent gastronomic evaluations, other than hierarchy and caste: mere (...) interpersonal variability with respect to brute gustatory sensations. After all, we all know about “supertasters and cilantro-haters”; how likely is it, though, that the interpersonal heterogeneity of gustatory sensation is limited to this one dimension? In this paper, I make the case that we should take this possibility more seriously, and offer some thoughts on how we might start getting a better handle on the nature and scope of interpersonal gustatory variability—including by suggesting some diagnostics that can help us get at (what I call) some of the “non-flavor dimensions” of our gustatory experience. I conclude by developing some implications for the prospects of an “alimentary aesthetics”: namely, that—should our gustatory experiences turn out to be quite heterogeneous—then they do not seem well-suited to serve as the basic ingredients of bona fide aesthetic judgment about food and drink. (shrink)

The central claim of the volume in which this chapter appears (*Fermented Landscapes*, ed. Colleen C. Myles, Univ. of Nebraska Press 2020) is that the chemical process of fermentation supplies an apt metaphor for understanding certain kinds of landscape change. The kinds of landscape change in question are, fortuitously, those often occasioned by commercial processes centered around fermentation itself: the commercial production of beer, wine, spirits, cider, cheese, and related fermented products. But what makes this metaphor apt? Which kinds of (...) landscape change are most fruitfully conceptualized as exhibiting “fermentation,” and how do they differ from other sorts of landscape change? What is it about fermentation-centered industries that effects fermentation-modeled landscape change, and when (if ever) do these industries contribute to other, different forms of landscape change? Is there any essential reason why fermentation-centered industries should create in their environs processes of transformation usefully characterized in terms of ferment? Or is this little more than a happy linguistic coincidence? In short: how much mileage do we get from this metaphor? This chapter offers a number of considerations germane to an evaluation of the “fermented landscapes” research paradigm—considerations to which readers may wish to remain alert as they study the contributions in this volume. (shrink)

Many theorists have recently observed that the response to the same-sex marriage controversy most congruent with basic liberal principles is neither the retention of the institution of marriage in its present form, nor its extension so as to include same-sex unions along with heterosexual ones, but rather the ‘dis-establishment’ of marriage. Less commonly observed, however, is the fact that there are two competing models for how the state might effect a regime of disestablished marriage. On the one hand, there is (...) a ‘deflationary’ approach, on which the state ceases to confer marital status, but does remain in the status-conferring business. On this approach, the state would still bestow a certain ‘thinner’, more ‘neutral’ legal status – as it does when it creates civil unions, for instance. Call this the ‘Status Model’ of disestablished marriage. On the other hand, there is an ‘eliminativist’ approach, on which the state ceases to confer any sort of status at all – not even the thin or neutral status of ‘civilly-unioned’. There simply are no registered domestic partnerships. What there is, is contract law, and individuals entering into contracts for life-partnership – contractual arrangements which might assume any of a wide variety of forms. Call this the ‘Contract Model’ of disestablished marriage. In this paper, I explore the merits of these competing models. After briefly discussing what it means to speak of ‘disestablishing marriage’, and examining the case for disestablishment, I proceed to consider the advantages and disadvantages of each model. My tentative conclusion is that the Contract Model is the one that best instantiates cardinal liberal virtues. (shrink)

Our topic is food that is "local, ethical, and sustainable." We defend a surprising claim about such a conception (at least, on certain ways of specifying its three central components): namely, that it may lend support to some varieties of “conscientious carnivorism.” We focus on an especially illustrative instance of (potentially) moral meat-eating: the case of Cinta Senese, a once-endangered pig that holds a special place in the cultural and environmental landscape in Tuscany, Italy. In Tuscany, Cinta Senese constitute a (...) robustly local food product (in the genealogical sense of "local"), where plausibly they lead quite worthwhile lives (in a welfarist sense of "worthwhile"). Further, the recent revival of their dwindling populations seemingly represents a “sustainability success” (in a conservationist sense). Thus, we argue that locavores with welfarist and conservationist proclivities may actually find that they have considerable reason to support, rather than to oppose, this form of animal agriculture – as well as others relevantly like it. (shrink)